I dunno, I auditioned a pair of 2ci's powered by an Audio Van Alstine something-or-other fed by a Naim CDsi CDP and found them to sound kinda boring compared to some Maggy 1.7s.
The 2ci is pretty laid back. The newer ones, starting with 2ce, have a more detailed tweeter. Lots of units out there in decent condition though, for fair prices.
On the even older 2c, which have been my main speakers for 10+ years, the HD650 comparison is probably more about being fairly good value overall and committing no major sins. I wouldn't say they sound the same, but speakers are just different from headphones. Generally laid back, non fatiguing, can sing loud when asked, sound good quiet. Excellent imaging, but small sweet spot. Highs are nice but not super crisp.
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