The answer depends: 1. how noisy are the USB ports on the computer or laptop being used? 2. how much resolution does the DAC have? 3. what is the noise floor of the DAC using native USB compared to the DAC SPDIF or Toslink input? 4. what is the scheduling jitter of the DAC USB driver? It is possible for a lower resolution DAC to minimize the differences between Singxer SU-1, Gustard U12 and Breeze DU-U8. I have in my task queue a measurement comparison of these three DDC with several DACs. Given my somewhat unpredictable schedule at the moment, completion may be weeks away or months away.